EXHIBIT 10.2

Published on October 7, 1997




Exhibit 10.16


COMMONWEALTH BIOTECHNOLOGIES, INC.
INCENTIVE STOCK OPTION AGREEMENT


THIS AGREEMENT, dated as of the ____________, 1997, between
COMMONWEALTH BIOTECHNOLOGIES, INC., a Virginia corporation (the "Company"), and
_____________ ("Optionee"), is made pursuant and subject to the provisions of
the Company's 1997 Stock Incentive Plan (the "Plan"), a copy of which is
attached and which is incorporated herein by reference. If there shall be any
inconsistency between this Agreement and the Plan, the terms of the Plan shall
control. All capitalized terms used herein that are defined in the Plan have the
same meanings given them in the Plan. All references herein to the Plan shall
mean the Plan in effect on the date hereof, as the same may be amended from time
to time in accordance with its terms.

1. Grant of Option. Pursuant to the Plan, the Company hereby grants to
Optionee, subject to the terms and conditions set forth herein and in the Plan,
the right and option (the "Option") to purchase from the Company all or any part
of an aggregate of __ shares of Common Stock (the "Option Shares") at the price
(the "Option Price") of $_________ per share, being not less than the Fair
Market Value per share of the Common Stock on the date of grant. Such Option
will be exercisable as hereinafter provided. This Option is intended to be an
Incentive Stock Option under Section 422 of the Code, but the Company does not
represent or warrant that the Option qualifies as such.

2. Terms and Conditions. This Option is subject to the following terms
and conditions:

(a) Expiration Date. The Expiration Date of this Option is
ten years after the date of this Agreement.

(b) Vesting; Exercise of Option. Subject to paragraphs 3,
4, 5, and 7, this Option shall become exercisable in accordance with following
schedule:

[vesting schedule to be inserted]

Once this Option has become exercisable in accordance with the
preceding schedule it shall continue to be exercisable with respect to such
Option Shares until the termination of Optionee's rights hereunder pursuant to
paragraphs 3, 4, 5, or 6, or until the Expiration Date, whichever occurs first.
A partial exercise of this Option shall not affect Optionee's right to exercise
this Option with respect to the remaining Option Shares, subject to the
conditions of the Plan and this Agreement. Any portion of this Option which has
not become exercisable on the effective date of termination of Optionee's
employment by the Company shall lapse.

(c) Method of Exercising and Payment. This Option shall be
exercised by written notice in the form attached hereto as Exhibit A, which is
incorporated herein by reference, delivered to the attention of the Company's
Secretary at the Company's principal office in Virginia. The exercise date shall
be the date such notice is received by the Company. Such notice shall be
accompanied by (i) cash payment or certified check equal to the Option Price
times the number of shares purchased (the "Exercise Price"), (ii) a certificate
representing Common Stock held for at least six months if acquired from the
Company and not subject to any restrictions with a Fair Market Value equal to
the Exercise Price, or (iii) instructions for the Company to withhold from the
purchased shares an amount with a Fair Market Value equal to the Exercise Price.
Upon acceptance of such notice and receipt of payment in full, the Company shall
cause to be issued a certificate representing the shares of Common Stock so
purchased.

(d) Nontransferability. This Option is nontransferable
except by will or by the laws of descent and distribution. During the
Optionee's lifetime, this Option may be exercised only by Optionee.

3. Exercise During Employment. Except as provided in Sections 4, 5 and
this Section 3, this Option may not be exercised (if otherwise exercisable under
Section 2) in whole or in part unless Optionee is then an employee of the
Company or an Affiliate or unless it is exercised, to the extent exercisable on
the date of termination under Section 2(b) above, within the period ending on
the earlier of the Expiration Date or the date 90 days after the effective date
of termination of Optionee's employment by the Company or an Affiliate;
provided, however, that in the event Optionee was terminated by the Company for
Cause, this Option may not be exercised at any time after the effective date of
such termination.

4. Exercise in the Event of Death. In the event Optionee dies while an
employee of the Company or an Affiliate and prior to the Expiration Date of this
Option, this Option may be exercised by Optionee's estate, or other person or
persons to whom his rights under this Option shall pass by will or the laws of
descent and distribution, to the extent exercisable on the date of his death
under Section 2(b) above, within one year after Optionee's death or until the
Expiration Date, whichever is earlier.

5. Exercise in the Event of Permanent and Total Disability. If Optionee
becomes permanently and totally Disabled (as determined in the sole and absolute
discretion of the Company) while an employee of the Company or an Affiliate and
prior to the Expiration Date of this Option, Optionee may exercise this Option,
to the extent exercisable on the date Optionee becomes permanently and totally
Disabled under Section 2(b) above, until the earlier of one year from the date
he ceases to be employed by the Company or an Affiliate due to such Disability
or the Expiration Date.

6. Extension if Optionee Subject to Section 16(b) of the 1934 Act.
Notwithstanding the foregoing paragraphs 3, 4, and 5, if the exercise of the
Option within the applicable time periods set forth above would subject the
Optionee to suit under Section 16(b) of the 1934 Act, the Option shall remain
exercisable to the extent permitted by law until the earliest to occur of (i)
the 10th day following the date on which the Optionee would no longer be subject
to such suit, (ii) the 190th day after the Optionee's termination of employment,
or (iii) the Expiration Date, provided that no additional vesting of the Option
shall occur during such periods. Any such extension of the period in which the
Option may be exercised may result in the Option ceasing to qualify as an
Incentive Stock Option and the Company makes no representation as to the tax
consequences of any such delayed exercise. The Optionee should consult with the
Optionee's own tax advisors as to the tax consequences to the Optionee of any
such delayed exercise.

7. $100,000 Limitation; Acceleration.

(a) Except as provided in Section 7(b) below, the aggregate
Fair Market Value of the stock with respect to which Optionee may exercise the
Option for the first time during any calendar year (determined as of the date
the Option was granted), together with any other Incentive Stock Options which
are exercisable by Optionee for the first time under any Company plan during any
such year, as determined in accordance with Code Section 422, shall not exceed
$100,000 (the "$100,000 Limitation"), other than as a result of an acceleration
of vesting due to a Change of Control transaction pursuant to Section 18 of the
Plan. In the event an acceleration of vesting causes the number of shares for
which the Option is first exercisable to exceed such amount, Section 7(b),
below, will apply. To the extent the exercisability of the Option is deferred by
reason of the $100,000 Limitation, the deferred portion of the Option will first
become exercisable in the first calendar year or years thereafter in which the
$100,000 Limitation would not be contravened.

(b) Notwithstanding any other provisions of this Agreement, in
the event an acceleration of vesting causes the number of shares for which the
Option is first exercisable to exceed the $100,000 Limitation, the Option shall
be deemed to be two options. The first Option shall be for the maximum number of
shares subject to the Option that can comply with the $100,000 Limitation
without causing the Option to be unexercisable as to vested shares. The second
Option, which shall not be treated as an Incentive Stock Option, shall be for
the balance of the shares subject to the Option and shall be exercisable on the
same terms and at the same time as set forth in this Agreement; provided,
however, that such shares shall become vested on the same date or dates as set
forth in this Agreement without regard to this paragraph. Unless Optionee
specifically elects to the contrary in his written notice of exercise, the first
option shall be deemed to be exercised first to the maximum possible extent and
then the second option shall be deemed to be exercised.

8. No Right to Continued Employment. This Option does not confer upon
Optionee any right with respect to continuance of employment by the Company or
an Affiliate, nor shall it interfere in any way with the right of the Company or
an Affiliate to terminate his employment at any time with or without cause.

9. Change in Capital Structure. The terms of this Option shall be
adjusted as provided in Section 17 of the Plan from time to time as the Board
determines is appropriate in the event of any subdivision of consolidation of
shares or other capital adjustment. Any and all new, substitute, or additional
securities or other property to which Optionee is entitled by reason of
ownership of the Option Shares shall be immediately subject to this Agreement
and shall be included in the definition of Option Shares for all purposes.

10. General Restrictions. Notwithstanding anything contained herein to
the contrary, no purported exercise of the Option shall be effective without the
written approval of the Company, which may be withheld to the extent that the
exercise of the Option, either individually or in the aggregate together with
the exercise of other previously exercised stock options and/or offers and sales
pursuant to any prior or contemplated offering of securities, would, in the sole
and absolute judgment of the Company, (i) require the filing of a registration
statement with the United States Securities and Exchange Commission or with the
securities commission of any state or (ii) violate any federal, state, or
foreign securities laws or other law or regulations. The Company shall avail
itself of any exemptions from registration contained in applicable federal and
state securities laws which are reasonably available to the Company on terms
which, in its sole and absolute discretion, it deems reasonable and not unduly
burdensome or costly. The Optionee shall deliver to the Company, prior to the
exercise of this Option, such information, representations and warranties as the
Company may reasonably request for the Company to be able to satisfy itself that
the Common Stock to be acquired pursuant to the exercise of the Option is being
acquired in accordance with the terms of an applicable exemption from the
securities registration requirements of applicable federal and state securities
laws. The Optionee is cautioned that the Option may not be exercisable unless
the foregoing conditions are satisfied. Accordingly, the Optionee may not be
able to exercise the Option when desired even though the Option is vested.

11. Tax Withholding. At the time the Option is exercised, in whole or
in part, or at any time thereafter as requested by the Company, the Optionee
hereby authorizes payroll withholding and otherwise agrees to make adequate
provision for Applicable Withholding Taxes, if any, which arise in connection
with the Option, including, without limitation, obligations arising upon (i) the
exercise, in whole or in part, of the Option, (ii) the transfer, in whole or in
part, of any Option Shares, (iii) the operation of any law or regulation
providing for the imputation of interest, or (iv) the lapsing of any restriction
with respect to any Option Shares. The Company shall have the right to withhold
or retain from any payment to Optionee (whether or not such payment is made
pursuant to this Option) or take such other action as is permissible under the
Plan which the Company deems necessary or appropriate to satisfy any Applicable
Withholding Taxes. The Optionee is cautioned that the Option is not exercisable
unless the Company's withholding obligations are satisfied.

12. Notice of Disqualifying Disposition. To obtain certain tax benefits
afforded to ISOs under Code Section 422, Optionee must hold the shares issued
upon the exercise of an ISO for two years after the date of grant of the option
and one year from the date of exercise. Optionee may be subject to the
alternative minimum tax at the time of exercise. Tax advice should be obtained
when exercising any option and before the disposition of the shares issued upon
the exercise of any option. By accepting the Option, Optionee hereby agrees to
promptly notify the Company's Chief Financial Officer if Optionee disposes of
any of the Option Shares within one year from the date he exercises all or part
of the Option or within two years of the date of grant of the Option.

13. Governing Law. This Agreement shall be governed by the laws of
the Commonwealth of Virginia without reference to the conflicts of laws
principles of any jurisdiction.

14. Optionee Bound by Plan. Optionee hereby acknowledges receipt of
a copy of the Plan and agrees to be bound by all the terms and provisions
thereof. Optionee hereby agrees to accept as binding, conclusive, and final
all decisions or interpretations of the Committee upon any questions arising
under this Agreement.

15. Legends. The Company may at any time place legends referencing the
terms of this Agreement and any applicable federal, state, or foreign securities
law restrictions on all certificates representing shares of stock subject to the
provisions of this Agreement. The Optionee shall, at the request of the Company,
promptly present to the Company any and all certificates representing shares
acquired pursuant to the Option in the possession of the Optionee in order to
carry out the provisions of this paragraph. Unless otherwise specified by the
Company, legends placed in such certificates may reference, but shall not be
limited to, (i) the 1933 Act requirements, (ii) the right of first refusal, and
(iii) the requirements of Code Section 422.

16. Binding Effect. Subject to the limitations stated above and in
the Plan, this Agreement shall be binding upon and inure to the benefit of
the legatees, distributees, and personal representatives of Optionee and
the successors of the Company.

17. Entire Agreement. This Agreement constitutes the entire agreement
between the parties with respect to the subject matter hereof and supersedes all
prior or contemporaneous written or oral agreements or understandings with
respect to the subject matter hereof. This Agreement may only be amended by a
writing signed by the party to be charged.

18. Legal Counsel. This Agreement has been prepared by LeClair Ryan, A
Professional Corporation (the "Firm"), as counsel to the Company, after full
disclosure of its representation of the Company to Optionee and with the consent
and direction of Optionee. Optionee has reviewed the contents of this Agreement
and fully understands its terms. Optionee acknowledges that he is fully aware of
his right to the advice of counsel independent from that of the Company, that
the Firm has advised him of such right and disclosed to him the risks in not
seeking such independent advice, and that he understands the potentially adverse
interests of the parties with respect to this Agreement. Optionee further
acknowledges that no representations have been made with respect to the income
or estate tax or other consequences of this Agreement to him and that he has
been advised of the importance of seeking independent advice of counsel with
respect to such consequences.

IN WITNESS WHEREOF, the Company has caused this Agreement to be signed
by a duly authorized officer, and Optionee has affixed his signature hereto.

COMMONWEALTH
BIOTECHNOLOGIES, INC.


By: _____________________________
Its: _____________________________
Date: ________________


___________________________________
______________, Optionee
Date:_________________



Exhibit A

NOTICE OF EXERCISE OF STOCK OPTION
TO PURCHASE COMMON STOCK OF COMMONWEALTH BIOTECHNOLOGIES, INC.


Name:___________________________

Address:_________________________

_________________________________

Date:____________________________



COMMONWEALTH BIOTECHNOLOGIES, INC..

Attention: Secretary

Re: Exercise of Stock Option

Gentlemen:

Subject to acceptance hereof in writing by Commonwealth
Biotechnologies, Inc. (the "Company") pursuant to the provisions of the
Commonwealth Biotechnologies, Inc. 1997 Stock Incentive Plan, I hereby elect to
exercise options granted to me to purchase ______________ shares of Common
Stock, no par value (the "Stock"), of the Company under the Incentive Stock
Option Agreement dated April 23, 1997 (the "Agreement"), at a price of
$__________ per share, for a total of $________ (the "Exercise Price"). Any
capitalized terms not defined herein shall have the meanings ascribed to them in
the Agreement.

I wish to pay for the Stock as follows:

[ ] By cash, certified check, or bank cashier's check, enclosed, for
$_______________ for the full Exercise Price, payable to Commonwealth
Biotechnologies, Inc.

[ ] By the enclosed certificate representing ____ shares of Common Stock
with a Fair Market Value equal to the Exercise Price ($ _________) that I have
held for at least six months (if I acquired them from the Company) and are not
subject to any restrictions.

[ ] By requesting that the Company withhold from the Stock I am purchasing
an amount with a Fair Market Value equal to the Exercise Price.

As soon as the Stock Certificate is registered as indicated below, please
deliver it to me at the above address.

I would like the Stock to be registered in the name(s) of
________________________________ as ____________________________________
(specify individual, joint tenants, tenants by the entirety, for the benefit of,
or other legal designation).

Very truly yours,



____________________________


AGREED TO AND ACCEPTED:

COMMONWEALTH BIOTECHNOLOGIES, INC..


By: _____________________________

Its: ____________________________

Number of Shares
Exercised: ______________________

Number of Shares
Remaining: ______________________